Vyhledat publikace
Bachořík, J.; Frydrych, I.; Gurská, S.; Dostál, Š.; Pokorný, J.; Džubák, P.; Hajdúch, M.; Urban, M.
New Synthetic Approach to C‑30 Ethers, Esters, and Amines of Betulin Using the Mitsunobu Reaction and Biological Evaluation of the Products
ACS Omega 2026, 11 (16), 24564-24579. DOI: 10.1021/acsomega.6c00716
Kristek, J.; Šťastná, N.; Pospíšil, J.
Base-Promoted C→N Carbonyl Shift Enables One-Step Access to aza-β-Lactams from α‑Heteroaryl-α-amino Esters
Org. Lett. 2026, 28 (20), 6318-6323. DOI: 10.1021/acs.orglett.6c01451
Sokhal, A. R.; Krajcovicova, S.; Iegre, J.; Brear, P.; De Fusco, C.; Glossop, P. A.; Cawkill, D.; Hyvonen, M.; Spring, D. R.
Selective Inhibition of CK2: Emerging Strategies and Future Directions
J. Med. Chem. 2026, 69 (15), 17584–17601. DOI: https://doi.org/10.1021/acs.jmedchem.6c00643
Kostadinova, K. A.; Venne, J. L.; Krajcovicova, S.*; Dodgson, J.; Hogendorf, W. F. J.; Nielsen, T. E. D.; Hymel, D.; Bolt, H.; Collinson, A.; Revell, J.; Spring, D. R.
Peptide Marriages: Modular Assembly of Multi-Agonist Therapeutics
Chem. Eur. J. 2026, – (-), e71280. DOI: https://doi.org/10.1002/chem.71280
Venne, J. L.; Krajcovicova, S.*; Davies, G.; Bolt, H.; Revell, J.; Spring, D. R.
Multicomponent Stapling of Glucagon-like Peptide-1 Enables Receptor-Guided PROTAC Delivery
Angew. Chem. Int. Ed. 2026, 65 (34), e9595531. DOI: https://doi.org/10.1002/anie.9595531
Krajcovicova, S.; Wharton, T.; Spring, D. R.
On-Resin Assembly of Cysteine-Reactive Linkers for Site-Selective Antibody Bioconjugation
Nature Protocols 2026, 21 (-), s41596-026-01376-4. DOI: https://doi.org/10.1038/s41596-026-01376-4
Day-Riley, S.; Krajcovicova, S.; Sokhal, A. R.; Venne, J. L.; Brear, P.; Hyvonen, M.; Whitehurst, B. C.; Carroll, J. S.; Spring, D. R.
Towards the Targeted Protein Degradation of CK2: Design and Synthesis of CAM4066-Based PROTACs
Beilstein J. Org. Chem. 2026, 22 (-), 611–619. DOI: https://doi.org/10.3762/bjoc.22.47
Bachořík, J.; Frydrych, I.; Gurská, S.; Dostál, Š.; Pokorný, J.; Přibylka, A.; Medvedíková, M.; Džubák, P.; Hajdúch, M.; Urban, M.
New C-30 secondary and tertiary amines of betulin with selective antiproliferative activity toward hematological malignancies – Synthesis and biological evaluation
Eur. J. Med. Chem. Rep. 2026, 17 (-), 100360. DOI: 10.1016/j.ejmcr.2026.100360
Urban, M.; Gonzalez, G.; Hodoň, J.; Strnad, M.
Terpenoid derivatives, pharmaceutical preparations containing these derivatives and their use in neuroprotection
Patent , US 12,636,299B2 , United States Patents and Trademark Office, 2026.
Papoušková, B.; Chrenko, D.; Hrouzek,P.; Zatloukalová, M.; Pospíšil, J.; Vacek*, J
Evidence of Nitro-fatty Acids in Microscopic Algae and Cyanobacteria
Phytochemistry Letters 2026, 76 (n/a), 104252 (1-5). DOI: 10.1016/j.phytol.2026.104252