Publikace

Borková, L.; Frydrych, I.; Vránová, B.; Jakubcová, N.; Lišková, B.; Gurská, S.; Džubák, P.; Pavliš, P.; Hajdúch, M.; Urban, M.
Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes
Eur. J. Med. Chem. 2022, 244 (N/A), 114850. DOI: 10.1016/j.ejmech.2022.114850

Hodoň, J.; Frydrych, I.; Lišková, B.; Das, V.; Ligasová, A.; Koberna, K.; Džubák, P.; Hajdúch, M.; Urban, M.
Triterpenoid pyridines and pyrazines – preparation, cytotoxic activity, mechanism of action, synthesis of prodrugs
56th Advances in Organic, Bioorganic, and Pharmaceutical Chemistry Liblice 2022, November 10 – 12, 2022, Špindlerův Mlýn, Přednáška .

Kúdelová, K.; Schwarzová, A.; Bachořík, H.; Urban, M.
Modified triterpenoides containing substituted triazole heterocycle
56th Advances in Organic, Bioorganic, and Pharmaceutical Chemistry Liblice 2022, November 10 – 12, 2022, Špindlerův Mlýn, Poster .

Orság, Š.; Hodoň, J.; Urban, M.
Synthesis and biological evaluation of C-30 modified lupane triterpenoids
56th Advances in Organic, Bioorganic, and Pharmaceutical Chemistry Liblice 2022, November 10 – 12, 2022, Špindlerův Mlýn, Poster .

Jurčeka, O.; Urban, M.; Gonzalez, G.; Strnad, M.
Synthesis of betulin derivatives modified at the position C-30 using cycloaddition reactions
56th Advances in Organic, Bioorganic, and Pharmaceutical Chemistry Liblice 2022, November 10 – 12, 2022, Špindlerův Mlýn, Poster .

Pokorný, J.; Olejníková, D.; Frydrych, I.; Lišková, B.; Džubák, P.; Hajdúch, M.; Urban, M.
Substituted azines and dienes of betulinic acid with selective cytotoxic activity to leukemia cells CCRF-CEM
56th Advances in Organic, Bioorganic, and Pharmaceutical Chemistry Liblice 2022, November 10 – 12, 2022, Špindlerův Mlýn, Poster .

Hodoň, J.; Frydrych, I.; Trhlíková, Z.; Pokorný, J.; Borková, L.; Benická, S.; Vlk, M.; Lišková, B.; Kubíčková, A.; Medvedíková, M.; Pisár, M.; Sarek, J.; Das, V.; Ligasová, A.; Koberna, K.; Džubák, P.; Hajdúch, M.; Urban, M.
Triterpenoid pyrazines and pyridines – synthesis, cytotoxicity, mechanism of action, preparation of prodrugs
Eur. J. Med. Chem. 2022, 243 (N/A), 114777. DOI: 10.1016/j.ejmech.2022.114777

Urban, M.; Gonzalez, G.; Hodoň, J.; Strnad, M.
Pentacyclic Triterpenes with Strong Neuroprotective Activity in SH-SY5Y Cells in Two Neurodegeneration Models
74. Sjezd Chemiků, September 4 – 7, 2022, Olomouc, Přednáška .

Tomanová, M.; Kozlanská, K.; Jorda, R.; Jedinák, L.; Havlíková, T.; Řezníčková, E.; Peřina, M.; Klener, P.; Dolníková, A.; Cankař, P.; Kryštof, V.
Synthesis and Structural Optimization of 2,7,9-Trisubstituted purin-8-ones as FLT3-ITD Inhibitors
Int. J. Mol. Sci. 2022, 23 (24), 16169. DOI: 10.3390/ijms232416169