Vyhledat publikace
Kazakova, A.; Frydrych, I.; Jakubcová, N.; Pokorný, J.; Lišková, B.; Gurská, S.; Buriánová, R.; Přibylka, A.; Džubák, P.; Hajdúch, M.; Urban, M.
Triterpenoid phthalimides as selective anti-cancer agents targeting mitochondrial apoptosis
Eur. J. Med. Chem. 2025, 283 (-), 117126 (1-23). DOI: 10.1016/j.ejmech.2024.117126
Frydrych, I.; Choma, B.; Slavíková, L.; Pokorný, J.; Jakubcová, N.; Ludha, S.; Gurská, S.; Řehulka, J.; Lišková, B.; Džubák, P.; Hajdúch, M. Urban, M.
Novel C-2 aromatic heterocycle-substituted triterpenoids inhibit hedgehog signaling in GLI1 overexpression cancer cells
ACS Omega 2025, 10 (10), 10617-10632. DOI: 10.1021/acsomega.4c11479
Frydrych, I.; Řehulka, J.; Slavíková, L.; Hodoň, J.; Pokorný, J.; Šidová, V.; Medvedíková, M.; Slavík, H.; Polishchuk, P.; Oždian, T.; Vrbková, J.; Šarek, J.; Džubák, P.; Hajdúch, M.; Urban, M.
Triterpenoid derivatives inhibit Gli-mediated transcription in human glioblastoma cell line via direct interaction with Gli1
J. Biol. Chem. 2025, 301 (9), 110372 (1-14). DOI: 10.1016/j.jbc.2025.110472
Urban, M.; Hodoň, J.; Koberna, K.; Ligasová, A.; Frydrych, I.
Pentacyclic triterpenoids with high selective cytotoxic activity and study of their mechanism of action
14Th Barrande-Vltava French-Czech Chemistry Meeting/Pardubice, August 31 – September 1, 2025, Pardubice (ČR), Zvaná přednáška .
Kazakova, A.; Frydrych, I.; Jakubcová, N; Pokorný. J.; Lišková, B.; Gurská, S.; Džubák, P.; Hajdúch, M.; Urban, M.
Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells – Synthesis, potency, and mitochondrial mechanism of action
Eur. J. Med. Chem. 2024, 269 (N/A), 116336 (1-16). DOI: 10.1016/j.ejmech.2024.116336
Urban, M.; Gonzalez, G.; Hodoň, J.; Strnad, M.
Terpenoid derivatives, pharmaceutical preparations containing these derivatives and their use in neuroprotection
patent , 309944 , Úřad Průmyslového Vlastnictví, 2024.
Porubsky, M. ; Hodon, J. ; Stanková, J.; Dzubák, P., ; Hajdúch, M. ; Urban, M.; Hlavác, J.
Near-infrared pH-switchable BODIPY photosensitizers for dual biotin/ cRGD targeted photodynamic therapy
Journal of Photochemistry and Photobiology B-Biology 2024, 2024 (259), 113010. DOI: 10.1016/j.jphotobiol.2024.113010
Urban, M.; Gonzalez, G.; Orság, Š; Jurčeka, O.; Strnad, M.
Betulin and Betulinic Acid Derivatives Have Significant Neuroprotective Activity in Salsolinol- and Glutamate- Induced Models of Neurodegeneration
ACS National Meeting Fall 2024, August 18 – 22, 2024, Denver (USA), poster .
Hodoň, J.; Frydrych, I.; Ligasová, A.; Koberna, K.; Džubák, P.; Hajdúch, M.,;Urban, M.
Triterpenoid pyridines and pyrazines and the study of their mechanism of action
ACS National Meeting Fall 2024, August 18 – 22, 2024, Denver (USA), poster .
Jurčeka, O.; Urban, M.
Modification of lupane derivatives at the position 17
ACS National Meeting Fall 2024, August 18 – 22, 2024, Denver (USA), poster .