Kazakova, A.; Frydrych, I.; Jakubcová, N.; Pokorný, J.; Lišková, B.; Gurská, S.; Buriánová, R.; Přibylka, A.; Džubák, P.; Hajdúch, M.; Urban, M.
Triterpenoid phthalimides as selective anti-cancer agents targeting mitochondrial apoptosis
Eur. J. Med. Chem. 2025, 283 (-), 117126 (1-23). DOI: 10.1016/j.ejmech.2024.117126
Frydrych, I.; Choma, B.; Slavíková, L.; Pokorný, J.; Jakubcová, N.; Ludha, S.; Gurská, S.; Řehulka, J.; Lišková, B.; Džubák, P.; Hajdúch, M. Urban, M.
Novel C-2 aromatic heterocycle-substituted triterpenoids inhibit hedgehog signaling in GLI1 overexpression cancer cells
ACS Omega 2025, 10 (10), 10617-10632. DOI: 10.1021/acsomega.4c11479
Kazakova, A.; Frydrych, I.; Jakubcová, N; Pokorný. J.; Lišková, B.; Gurská, S.; Džubák, P.; Hajdúch, M.; Urban, M.
Novel triterpenoid pyrones, phthalimides and phthalates are selectively cytotoxic in CCRF-CEM cancer cells – Synthesis, potency, and mitochondrial mechanism of action
Eur. J. Med. Chem. 2024, 269 (N/A), 116336 (1-16). DOI: 10.1016/j.ejmech.2024.116336
Porubsky, M. ; Hodon, J. ; Stanková, J.; Dzubák, P., ; Hajdúch, M. ; Urban, M.; Hlavác, J.
Near-infrared pH-switchable BODIPY photosensitizers for dual biotin/ cRGD targeted photodynamic therapy
Journal of Photochemistry and Photobiology B-Biology 2024, 2024 (259), 113010. DOI: 10.1016/j.jphotobiol.2024.113010
Borková, L.; Frydrych, I.; Vránová, B.; Jakubcová, N.; Lišková, B.; Gurská, S.; Džubák, P.; Pavliš, P.; Hajdúch, M.; Urban, M.
Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes
Eur. J. Med. Chem. 2022, 244 (N/A), 114850. DOI: 10.1016/j.ejmech.2022.114850
Hodoň, J.; Frydrych, I.; Trhlíková, Z.; Pokorný, J.; Borková, L.; Benická, S.; Vlk, M.; Lišková, B.; Kubíčková, A.; Medvedíková, M.; Pisár, M.; Sarek, J.; Das, V.; Ligasová, A.; Koberna, K.; Džubák, P.; Hajdúch, M.; Urban, M.
Triterpenoid pyrazines and pyridines – synthesis, cytotoxicity, mechanism of action, preparation of prodrugs
Eur. J. Med. Chem. 2022, 243 (N/A), 114777. DOI: 10.1016/j.ejmech.2022.114777
Chasák, J.; Šlachtová, V.; Urban, M.; Brulíková, L.*
Squaric acid analogues in medicinal chemistry
Eur. J. Med. Chem. 2021, 209 (-), 112872 (1-23). DOI: 10.1016/j.ejmech.2020.112872
Urban, M.; Šlachtová, V.; Brulíková, L.*
Small organic molecules targeting the energy metabolism of Mycobacterium tuberculosis
Eur. J. Med. Chem. 2021, 212 (-), 113139 (1-17). DOI: 10.1016/j.ejmech.2020.113139
Gonzalez, G.; Hodoň, J.; Kazakova, A.; D’Acunto, C. W.; Kaňovský, P.; Urban, M.; Strnad, M.
Novel pentacyclic triterpenes exhibiting strong neuroprotective activity in SH-SY5Y cells in salsolinol- and glutamate-induced neurodegeneration models
Eur. J. Med. Chem. 2021, 213 (n/a), 113168. DOI: 10.1016/j.ejmech.2021.113168
Bachořík, J.; Urban, M.
Biocatalysis in the Chemistry of Lupane Triterpenoids
Molecules 2021, 26 (8), 2271(1-26). DOI: 10.3390/molecules26082271