Vyhledat publikace
Sokhal, A. R.; Krajcovicova, S.; Iegre, J.; Brear, P.; De Fusco, C.; Glossop, P. A.; Cawkill, D.; Hyvonen, M.; Spring, D. R.
Selective Inhibition of CK2: Emerging Strategies and Future Directions
J. Med. Chem. 2026, 69 (15), 17584–17601. DOI: https://doi.org/10.1021/acs.jmedchem.6c00643
Kostadinova, K. A.; Venne, J. L.; Krajcovicova, S.*; Dodgson, J.; Hogendorf, W. F. J.; Nielsen, T. E. D.; Hymel, D.; Bolt, H.; Collinson, A.; Revell, J.; Spring, D. R.
Peptide Marriages: Modular Assembly of Multi-Agonist Therapeutics
Chem. Eur. J. 2026, – (-), e71280. DOI: https://doi.org/10.1002/chem.71280
Venne, J. L.; Krajcovicova, S.*; Davies, G.; Bolt, H.; Revell, J.; Spring, D. R.
Multicomponent Stapling of Glucagon-like Peptide-1 Enables Receptor-Guided PROTAC Delivery
Angew. Chem. Int. Ed. 2026, 65 (34), e9595531. DOI: https://doi.org/10.1002/anie.9595531
Krajcovicova, S.; Wharton, T.; Spring, D. R.
On-Resin Assembly of Cysteine-Reactive Linkers for Site-Selective Antibody Bioconjugation
Nature Protocols 2026, 21 (-), s41596-026-01376-4. DOI: https://doi.org/10.1038/s41596-026-01376-4
Day-Riley, S.; Krajcovicova, S.; Sokhal, A. R.; Venne, J. L.; Brear, P.; Hyvonen, M.; Whitehurst, B. C.; Carroll, J. S.; Spring, D. R.
Towards the Targeted Protein Degradation of CK2: Design and Synthesis of CAM4066-Based PROTACs
Beilstein J. Org. Chem. 2026, 22 (-), 611–619. DOI: https://doi.org/10.3762/bjoc.22.47
Krajcovicova, S.; Wharton, T.; Driscoll, C. L.; King, T. A.; Howarth, M. R.; Spring, D. R.
A Platform for SpyCatcher Conjugation to Native Antibodies
Chem. Sci. 2025, 2025 (16), 10602-10609. DOI: https://doi.org/10.1039/D5SC02286J
Sydenham J. D. ; Seki, H.; Krajcovicova, S.; Schober, T.; Zeng, L.; Deingruber, T. ; Spring D. R.
Site-Selective Peptide Functionalisation Mediated via Vinyl-Triazine Linchpins
Chem. Commun. 2024, 60 (-), 706-709. DOI: 10.1039/D3CC05213C
Krajcovicova, S.*; Spring, D. R.
Tryptophan in Multicomponent Petasis Reactions for Peptide Stapling and Late-Stage Functionalisation
Angew. Chem. Int. Ed. 2023, 62 (-), e202307782. DOI: 10.1002/anie.202307782
King, T.; Walsh, S.; Kapun, M.; Wharton, T.; Krajcovicova, S.; Glossop, M.; Spring, D. R.
Disulfide re-bridging reagents for single-payload antibody-drug conjugates
Chem. Commun. 2023, 59 (-), 9868-9871. DOI: 10.1039/D3CC02980H
Iegre, J.‡; Krajcovicova, S.‡; Gunnarsson, A.; Wissler, L.; Kaeck, H.; Luchniak, A.; Tangefjord, S.; Narjes, F.; Spring, D. R.
A cell-active cyclic peptide targeting the Nrf2/Keap1 protein–protein interaction
Chem. Sci. 2023, 14 (-), 10800-10805. DOI: 10.1039/D3SC04083F