Autor: Hradil, P.; Krejčí, P.; Hlaváč, J.; Wiedermannová, I.; Lyčka, A.; Bertolasi, V.
Název práce v češtině: Synthesis, NMR spectra and X-ray data of chloro and dichloro derivatives of 3-hydroxy-2-phenylquinolin-4(1H)-ones and their cytostatic activity

Studentská publikace: ne

Abstrakt česky: As known, some derivatives of quinolin-4(1H)-one possess interesting biological properties. The biological and cytostactic activity of 2-substituted 3-hydroxyquinolin-4(1H)-ones has not been reported yet. In this paper the synthesis of a series of chloro and dichloro 2-phenyl-3-hydroxyquinolin-4(1H)- ones and their characterization by NMR spectra and X-ray data is described. Their cytostatic properties have been evaluated and the results are reported.

Jazyk v originále: čeština
Název časopisu: J. Heterocyclic Chem.
Rok: 2004
Svazek (ročník): 3
Číslo časopisu v rámci uvedeného svazku: 41
Strana od-do: 375-379

Q1: ne