Course Guarantor

Marek Šebela

Form of course completion:

Exam

Annotation:

Content:

• Enzyme models and mimics
• Functionalized cyclodextrines as enzyme catalysts
• Synthetic polymers and dendrimers as a part of artificial enzymes
• Natural polypeptides functionalization
• Metalocomplexes as catalysts
• Aminotransferases, decarboxylases and hydrolases mimics
• Directed halogenations
• Hydroxylations as mimics of cytochrome P450 reactions
• Antibodies as artificial enzymes
• Carbon-based, metal-based and metal oxide-based nanozymes

Literature:

• Ronald Breslow (Ed.): Artificial enzymes. Wiley-VCH, 2005. ISBN 13 978-3-527-31165-1
• Xiaoyu Wang, Wenjing Guo, Yihui Hu, Jiangjiexing Wu, Hui Wei: Nanozymes: next wave of artificial enzymes. Springer, 2016. ISBN 978-3-662-53066-5