Branch of Study Guarantor
prof. RNDr. Jan Hlaváč, Ph.D.
The graduate has the theoretical background in all areas of chemistry, including the laboratory techniques, being able to work with chemical literature and databases, find relevant information, plan syntheses, synthesise and analyse new compounds by using modern methods of synthesis and structural analysis. The graduate is familiar with reaction mechanisms and is able to apply this knowledge in compounds preparation. In practice, the graduates can do research aimed to the synthesis of new compounds and successfully and creatively solve the problems. The graduates find jobs mainly in chemical and pharmaceutical industry.
Education Aims of the Ph.D. study
The aim of the Ph.D. study of organic chemistry is the preparation of highly qualified scientists in the field of organic chemistry. Throughout the course students will be introduced to the latest knowledge in the field of organic chemistry, such as the synthesis of individual structural types of organic molecules and their functional derivatives, the determination of the structure using analytical methods, the study of reactivity and physico-chemical properties. Students are acquainted with both classical and modern methods of synthesis of organic compounds, using various analytical techniques and methods of determining the course of chemical reactions. Particular attention is paid to the study of heterocyclic compounds and the study of natural and biologically active compounds. Students are led to solve the assigned project from organic chemistry. During the course students will be able to improve their English language skills so that they can communicate, write publications and lecture at international conferences. The main focus of the study is work on experiments under the guidance of experienced and qualified university teachers of the Department of Organic Chemistry. Students are involved in projects that are addressed by departmental staff in the field of synthesis of substances with potential biological activity and also in the significant development of solid phase synthesis and combinatorial chemistry.
Successful passing an entrance exam.
Profile of the Graduate
Graduate of the Doctoral Study of Organic Chemistry possesses all basic fields of chemistry (inorganic, physical, analytical, biochemistry, environmental chemistry, macromolecular chemistry) and also has a broad knowledge of organic chemistry and is able to orientate in laboratory techniques of the whole chemistry. He is able to work with chemical information, orientate himself in chemical literature (secondary and primary sources, databases), search for the required information, including using computer methods in commercially available databases. The graduate is able to correlate the relationship between the structure and properties of the prepared compounds and can independently plan the synthesis of the new compounds, possibly critically assess the syntheses already proposed. Controls laboratory methods of organic chemistry in practice, including modern methods of synthesis. Applying their knowledge of physical organic methods, they are able to analyze synthesized unknown compounds; both analysis of purity and eventual purification of individual components using special analytical separation methods (HPLC, TLC, LC). Additionally perfectly manages to determine the structure of substances based on the use of methods of structural analysis (UV / VIS, IR, MS, NMR (including advanced experiments). Graduates are able to apply and orient themselves in modern information technologies and also are able to acquire and process the latest scientific information from the world of electronic databases. Controls data collection and processing to prepare custom graphical and value-based presentations. Knowledge of English is at a level that can communicate, write, and present results in this language. The study is conducted in such a way that the graduate is maximally adaptable and able to orient himself in the new trends of the field, which will bring the progressing time. Graduates will apply for further academic careers at universities, as employees of state and private research laboratories in the Czech Republic and abroad. They can successfully perform tasks in laboratories with a focus on the development of substances with potential biological activity, pharmacies, polymer compounds, new materials, etc. Graduates have all the prerequisites to become leaders and organizational staff of research teams.
Assumptions of Applicability
Graduate fulfil all criteria for employment in state as well as private institutions existing in branch of chemical and pharmaceutical industry. Positions can be typically found in laboratories focused on development of organic synthesis, preparation of organic substances including drugs, material modification, laboratories focused on isolation of compounds and study of their structure, laboratories focused on development of diagnostic tools, etc.
Head of research and development laboratories focused on the preparation of organic compounds and modification of materials.