Course Guarantor and teacher

Miroslav Soural; Antonín Lyčka

Form of course completion:

Exam

Annotation:

Theory of some NMR experiments used to solve a structure of organic compounds and monitoring of some intra or intermolecular actions. Application, scope and accuracy of measurements.

Content:

• Basic principles of NMR
• Principles of 2D experiments (homonuclear and heteronuclear)
• Overhauser spectroscopy, spin-lock experiments – 3D NMR (TOCSY, ROESY, HOESY
• Heteronuclear NMR spectroscopy (N15, O17, Si29, B11)
• Solid-state NMR spectroscopy

Literature:

• Gunther H.: NMR Spectroscopy: Basic Principles, Concepts and Applications in Chemistry, Wiley-VCH; 3 edition, Germany, 2013
• Claridge, T. D. W. High-Resolution NMR Techniques in Organic Chemistry. Pergamon, Amsterdam, 1999.
• Weber, U; Thiele, H. NMR-Spectroscopy: Modern Spectral Analysis. John Wiley & Sons, New York, USA, 1998.
• Berger, S.; Braun, S. 200 and More NMR Experiments: A Practical Course. John Wiley & Sons, New York, USA, 2004.